Risiko Kandidiasis Serviks pada Wanita Usia Subur Akseptor Kontrasepsi Hormonal

  • Ni Wayan Armerinayanti Warmadewa University
  • Desak Putu Oki Lestari FKIK Unwar

Abstract

Abstrak Kontrasepsi Hormonal merupakan salah satu metode kontrasepsi yang paling diminati oleh Wanita Usia Subur (WUS) di Indonesia termasuk di Bali. Dewasa ini mulai timbul pro dan kontra mengenai penggunaan kontrasepsi hormonal terkait berbagai efek samping yang ditimbulkan, salah satunya dikatakan berkaitan dengan kandidiasis serviks. Tujuan penelitian ini adalah untuk mengetahui risiko kandidiasis serviks pada WUS akseptor kontrasepsi hormonal. Penelitian ini menggunakan rancangan case control yang disarangkan pada penelitian pap smear (nested case control). Kemudian akan dibandingkan seberapa besar efek paparan kontrasepsi hormonal antara kelompok kasus (kandidiasis serviks) dengan kelompok kontrol (non kandidiasis serviks) secara deskriptif analitik melalui uji statistik chi-square dengan p<0.05 dan confident interval (CI) 95%. Hasil analisis tersebut menunjukkan perbedaaan yang bermakna terjadinya kandidiasis serviks antara akseptor kontrasepsi hormonal dengan non hormonal, dengan nilai p= 0,000 (p<0.001), OR= 6,435. Abstract [Risk of Services Candidates in Women Age Hospital Acceptor Hormonal Contracteption] Hormonal contraceptive is one kind of contraceptive methods that mostly choosed by reproductive age women in Indonesia, especially in Bali. Nowadays, there was some polemic about hormonal contraceptive related it side effects, include cervical candidiasis. The aims of this study was to explore cervical candidiasis risk among reproductive woman hormonal contraceptive users. Methode: This study used nested case control design which then compare about hormonal contraceptive effect between cases group (cervical candidiasis) and control group (non cervical candidiasis) by descriptibe analysis of chi-square statistic test, p< 0.05 and confident interval (CI) 95%. Result: There was significant differenciate cervical candidiasis between hormonal contraceptive users and non hormonal contraceptive users, p=0.000 (p<0.001), OR=6.345, CI=95%. Discussion: Cervical candidiasis risk among hormonal contraceptive users related of estrogen and progesterone component which can supporting candida species growth.

Author Biographies

Ni Wayan Armerinayanti, Warmadewa University
Anatomic Pathology
Desak Putu Oki Lestari, FKIK Unwar
Patologi Anatomi Penata Muda (IIIB)

References

Anonim. 2009. Reproductive health Indicator: World Health Organization. Geneva. pp. 9-13

Badan Kependudukan dan Keluarga Berencana Nasional (BKKBN). 2007. Buletin Program KB Nasional. Direktorat Pelaporan dan Statistik BKKBN.Jakarta. pp 2-8

Badan Kependudukan dan Keluarga Berencana Nasional (BKKBN). 2011. Laporan Umpan Balik Hasil Pelaksanaan Subsistem Pencatatan dan Pelaporan Pelayanan Kontrasepsi. Direktorat Pelaporan dan Statistik BKKBN. Jakarta. pp 8-11

Bekker, E. 2015. Connection Between Chronic Yeast Infection And Hormonal Imbalance. Modpathol Journal. 5(3). 1-12

Casari, E. 2010. Gardnerella, Trichomonas vaginalis, Candida. Microbio J. 4. 1-6

Cheng, G; Yeater, KM; Hoyer, LL. 2006. Cellular and Molecular Biology of Candida Albicans Estrogen Response; Eucaryotic Cell American Society for Microbiology. Vol 5. 180-190

Chrousos, GP.2007. The Gonadal Hormone and Inhibitors on Katzung Basic and Clinical Pharmacology. 10thed. The McGraw-Hill Co. Inc. Philadelphia. pp.664-71

Dhont, M. 2010. History of Oral Contraception. The European journal of Contraception and Reproductive Health Care. 15(52).15-18

Ekpenyong ,CE, Inyang-Etoh EC, akpan UP, Ibu JO, Daniel NE. 2012. Recurrent Vulvovaginal Candidiosis Among Young Women In South Eastern Nigeria; The role of Lifestyle and Health Care Practices; Int J STD AIDS.23(10). 704-9

Hamad, W. 2014. Estrogen Treatment Predisposes to Severe And Persistent Vaginal Candidiasis in Diabetic Mice. BioMed Central Journal of Diabetes and Metabolic Disorders. 12(10). 1-7

Infodatin, 2014. Pusat Data dan Informasi Kementerian Kesehatan. Jakarta. pp.1-6

Kiley, J, Hammond, C. 2007. Combined Oral Contraceptives; A Comprehensive Review. Clin. Obst. Gyn, 50(2). 868-77

Shahinfar, S., Nemanpour, B. 2016. The Relationship Between Contraceptive methods and Common Vaginal Infections. Women’s health Bull. Inpress e40793. Pp. 1-5.

Solomon C., Nayar. R. 2004. The Betesda System for Reporting Cervical Cytology. Springer. pp 1-11

Susilowati, E. 2011. KB Suntik 3 Bulan dengan Efek Samping Gangguan Haid dan Penanganannya. Semarang. pp.1-8

Trussell, J. 2007. Contraceptive Efficacy. In Hatcher, R.A., et al; Contraceptive Technology; Ardent Media. New York. pp 1-12

Varney, Hellen et al. 2006. Buku Ajar Asuhan Kebidanan.Jakarta. 4(1). 20-31

Wagner, RJ. 2012. Probiotic Lactobacillus and Estrogen effect on Vaginal Epithelial Gene Expression Responses to Candida Albicans. J Biomed Sci. 5(2).19-58

Yusuf, MD., et al. 2007. Evaluation of the Effect of Contraceptives on Prevalence of Candida Species on Vaginal Candidiasis in Dhaka, Bangladesh. Bangladesh J med Microbiol. 01 (02). 61-64

Widodo, F.Y. 2014. Efek Pemakaian Kontrasepsi Kombinasi Terhadap Kadar Glukosa Darah. Surabaya. pp 1-9

Wiknjosastro, H. 2007. Ilmu Kandungan. Yayasan Bina Pustaka. Jakarta. pp 534-575

Published
2018-06-01
How to Cite
Armerinayanti, N. W., & Lestari, D. P. O. (2018). Risiko Kandidiasis Serviks pada Wanita Usia Subur Akseptor Kontrasepsi Hormonal. WMJ (Warmadewa Medical Journal), 3(1), 21-26. https://doi.org/10.22225/wmj.3.1.640.21-26
Section
Articles
Abstract viewed = 165 times
PDF (Bahasa Indonesia) downloaded = 144 times